GW-FEAST: Difference between revisions

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The GW Federated Ecosystems for Analytics and Standardized Technologies (GW-FEAST) project is part of the ARPA-H FEAST performer team initiative that includes academic and industry partners. The goal of the ARPA-H performer teams is “to create bridges across data silos to make health data more accessible and usable”.
Federated Ecosystems for Analytics and Standardized Technologies (FEAST) is a cloud-based, agile bioinformatics and data analysis platform under development through the ARPA-H Biomedical Data Fabric (BDF) toolbox program. The project is led by [https://dnahive.com DNA-HIVE] and other funded collaborators include Cornell University, Vanderbilt University, Georgetown University, European Bioinformatic Institute, and Kaiser Permanente. Our team is responsible for the GW instance of FEAST (GW-FEAST) and for co-leading the project with DNA-HIVE. This project is part of the ARPA-H FEAST performer team initiative to create bridges across data silos and make health data more accessible and usable.  


ARPA-H FEAST offers two major innovations for digital healthcare ecosystems addressing current challenges.
Several hospitals and cancer centers will have a FEAST platform, which enables cross-site data analysis without the need to export or transform the data. Currently, large chunks of data are used by insurance companies, pharmaceutical companies, and others for research and development purposes. The FEAST platform, which is particularly strong with noisy, real-world data, aims to enable more precise data selection for research use while preserving patient privacy. When clinical data is submitted to the suite of tools, submission is handled via the HL7 FHIR protocol, ensuring only authorized parties ever have access to protected data. Models that provide update mechanisms such as online training will be updated appropriately without retaining any personally identifiable information (PII). Thus, these tools support federated data sets and training without ever retaining clinical PII within the system. All services are treated as independent microservices through containerization within docker containers.  


1) Agnostic federation across multiple data sources allows DNA HIVE to move computations to data instead of moving data to computation; this avoids violation of regulations for data export while using all data.  
==== GW-FEAST Project Architecture ====
[[File:GW-FEAST_Architecture.png|frameless|1077x1077px]]
This figure depicts the current GW instance of FEAST and is subject to change throughout the life of the project.


2) Agnostic harmonization through self-standardizing protocols enables computers to handshake and find appropriate standard transformations as per need without prior need for expensive standardization efforts at sites.
==== GW-FEAST Data Access Portal ====
GW-FEAST data is access-controlled. To gain access please email mazumder-lab@gwu.edu
For users who have access please connect to GW VPN and then go to the [https://feast.mgpc.biochemistry.gwu.edu/dsviewer '''data access portal'''] and log in.

Latest revision as of 14:41, 2 January 2025

Federated Ecosystems for Analytics and Standardized Technologies (FEAST) is a cloud-based, agile bioinformatics and data analysis platform under development through the ARPA-H Biomedical Data Fabric (BDF) toolbox program. The project is led by DNA-HIVE and other funded collaborators include Cornell University, Vanderbilt University, Georgetown University, European Bioinformatic Institute, and Kaiser Permanente. Our team is responsible for the GW instance of FEAST (GW-FEAST) and for co-leading the project with DNA-HIVE. This project is part of the ARPA-H FEAST performer team initiative to create bridges across data silos and make health data more accessible and usable.

Several hospitals and cancer centers will have a FEAST platform, which enables cross-site data analysis without the need to export or transform the data. Currently, large chunks of data are used by insurance companies, pharmaceutical companies, and others for research and development purposes. The FEAST platform, which is particularly strong with noisy, real-world data, aims to enable more precise data selection for research use while preserving patient privacy. When clinical data is submitted to the suite of tools, submission is handled via the HL7 FHIR protocol, ensuring only authorized parties ever have access to protected data. Models that provide update mechanisms such as online training will be updated appropriately without retaining any personally identifiable information (PII). Thus, these tools support federated data sets and training without ever retaining clinical PII within the system. All services are treated as independent microservices through containerization within docker containers.

GW-FEAST Project Architecture

This figure depicts the current GW instance of FEAST and is subject to change throughout the life of the project.

GW-FEAST Data Access Portal

GW-FEAST data is access-controlled. To gain access please email mazumder-lab@gwu.edu For users who have access please connect to GW VPN and then go to the data access portal and log in.